+ Filter
Loading...
Custom Services order now ship next day

DENND3

Loading...

Anti-DENND3 Products

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

More Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

For Research Use Only. Not For Clinical Use.


Background

Guanine nucleotide exchange factor (GEF) activating RAB12. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form. Thereby, may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor.
Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Alveolar cells type 1, Microglial cells)

Immune cell specificity

Immune cell enhanced (neutrophil, eosinophil)

Cell line specificity

Cell line enhanced (HDLM-2, HeLa, U-937)

Interaction

Forms oligomers. Interacts with 6 of the 7 known isoforms of 14-3-3 proteins.

Molecular function

Guanine-nucleotide releasing factor

More Types Infomation
Go to compare

Go to compare