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DR5 & FAP
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- PE-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer (MHC-CN0661)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: PE
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- APC-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer (MHC-CN0662)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: APC
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- FITC-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer (MHC-CN0663)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: FITC
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- H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer (MHC-CN0664)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: Unconjugated
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- PE-A*02:01/Human FAP (GLFKCGIAV) MHC Tetramer (MHC-CN0665)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: PE
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- APC-A*02:01/Human FAP (GLFKCGIAV) MHC Tetramer (MHC-CN0666)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: APC
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- FITC-A*02:01/Human FAP (GLFKCGIAV) MHC Tetramer (MHC-CN0667)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: FITC
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- A*02:01/Human FAP (GLFKCGIAV) MHC Tetramer (MHC-CN0668)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: Unconjugated
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- PE-A*02:01/Human FAP (ALVCYGPGI) MHC Tetramer (MHC-CN0669)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: PE
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- APC-A*02:01/Human FAP (ALVCYGPGI) MHC Tetramer (MHC-CN0670)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: APC
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- FITC-A*02:01/Human FAP (ALVCYGPGI) MHC Tetramer (MHC-CN0671)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: FITC
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- A*02:01/Human FAP (ALVCYGPGI) MHC Tetramer (MHC-CN0672)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: Unconjugated
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
In association with DPP4 is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May have a role in tissue remodeling during development and wound healing, and may contribute to invasiveness in malignant cancers.
