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DR5 & FAP
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Anti-DR5 & FAP Recombinant Antibody Products
- A*02:01/Human FAP (ALVCYGPGI) MHC Tetramer (MHC-CN0672)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: Unconjugated
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- FITC-A*02:01/Human FAP (ALVCYGPGI) MHC Tetramer (MHC-CN0671)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: FITC
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- APC-A*02:01/Human FAP (ALVCYGPGI) MHC Tetramer (MHC-CN0670)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: APC
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- PE-A*02:01/Human FAP (ALVCYGPGI) MHC Tetramer (MHC-CN0669)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: PE
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- A*02:01/Human FAP (GLFKCGIAV) MHC Tetramer (MHC-CN0668)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: Unconjugated
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- FITC-A*02:01/Human FAP (GLFKCGIAV) MHC Tetramer (MHC-CN0667)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: FITC
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- H-2Kb/Human muFAP alpha (SDYYFSWL) MHC Pentamer (MHC-YF573)
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- Class: Class I
- Antigen: muFAP alpha
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- A*02:01/Human FAP alpha (ALVCYGPGI) MHC Pentamer (MHC-YF432)
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- Class: Class I
- Antigen: FAP alpha
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: Unlabeled, Biotin, R-PE, APC
Compare
- A*02:01/Human FAP (GLFKCGIAV) MHC Pentamer (MHC-YF431)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: Unlabeled, Biotin, R-PE, APC
Compare
- APC-A*02:01/Human FAP (GLFKCGIAV) MHC Tetramer (MHC-CN0666)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: APC
Compare
- PE-A*02:01/Human FAP (GLFKCGIAV) MHC Tetramer (MHC-CN0665)
-
- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: PE
Compare
- H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer (MHC-CN0664)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: Unconjugated
Compare
- FITC-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer (MHC-CN0663)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: FITC
Compare
- APC-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer (MHC-CN0662)
-
- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: APC
Compare
- PE-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer (MHC-CN0661)
-
- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: PE
Compare
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.