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DR5 & FAP
Loading...Anti-DR5 & FAP Products
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- Antibody Host: Human
- Antibody Reactivity: Human
- Mouse Anti-FAP Recombinant Antibody (HPAB-0171-CN) (HPAB-0171-CN)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG2a
- Application: ELISA
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, IP, FC, FuncS, Neut, IF, WB
- Human Anti-FAP Recombinant Antibody (TAB-024WM) (TAB-024WM)
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- Species Reactivity: Human, Mouse, Monkey
- Type: Human IgG1
- Application: IHC, ELISA, FC, IF
- Human Anti-FAP Recombinant Antibody (clone ESC14) (HPAB-0175-CN)
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: ELISA, WB, FC, IHC, IP
- Mouse Anti-FAP Recombinant Antibody (clone F19) (HPAB-A1368-YJ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FuncS, RIA, IP, IF, IHC, IA, Block
- Human Anti-DR5 Recombinant Antibody (clone YC037) (MOB-0245MC)
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- Species Reactivity: Human
- Application: ELISA, WB, IHC, FuncS
- Human Anti-FAP Recombinant Antibody (HPAB-0668-YJ) (HPAB-0668-YJ)
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: ELISA, Inhib, IHC, IF, FuncS
- Human Anti-FAP Recombinant Antibody; Fab Fragment (TAB-024WM-F(E)) (TAB-024WM-F(E))
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- Species Reactivity: Human, Mouse, Monkey
- Type: Human Fab
- Application: ELISA, FC, IF
- Mouse Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0171-CN-F(E)) (HPAB-0171-CN-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA
- Human Anti-FAP Recombinant Antibody (clone cF19); Fab Fragment (HPAB-0176-CN-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, FC, IHC, IP, IF
- Human Anti-DR5 Recombinant Antibody (clone 304) (FAMAB-1708CQ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: RIA, FuncS, ELISA
- Human Anti-DR5 Antibody (clone KMTR1), mRNA (FAMAB-1693CQ-mRNA)
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- Species Reactivity: Human
- Human Anti-DR5 Antibody, mRNA (FAMAB-1707CQ-mRNA) (FAMAB-1707CQ-mRNA)
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- Species Reactivity: Human
- Human Anti-FAP Recombinant Antibody (HPAB-0170-CN) (HPAB-0170-CN)
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human IgG
- Application: ELISA, IF
- Rabbit Anti-FAP Recombinant Antibody (VS-0723-WK245) (VS-0723-WK245)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, FC
- Human Anti-FAP Recombinant Antibody (HPAB-0173-CN) (HPAB-0173-CN)
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized IgG1, κ
- Application: ELISA
- Rabbit Anti-FAP Polyclonal Antibody (MRO-1853-CN) (MRO-1853-CN)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, FC
- AbPlus™ Anti-FAP Magnetic Beads (ESC14) (VS-0424-XY97)
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- Target: FAP
- Target Species: Human, Mouse
- Application: IP, Protein Purification
- Human Anti-FAP Recombinant Antibody (HPAB-2062-FY) (HPAB-2062-FY)
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: FC
- Human Anti-FAP Recombinant Antibody; scFv Fragment (TAB-024WM-S(P)) (TAB-024WM-S(P))
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- Species Reactivity: Human, Mouse, Monkey
- Type: Human scFv
- Application: ELISA, FC, IF
- Recombinant Mouse Anti-Human FAP Antibody (MOB-1515MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
- Human Anti-FAP Recombinant Antibody (clone 18) (HPAB-A1374-YJ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, FC, Inhib
- Human Anti-DR5 Recombinant Antibody (clone KMTR1) (FAMAB-1693CQ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: RIA, FuncS, ELISA
- Human Anti-DR5 Recombinant Antibody (FAMAB-1707CQ) (FAMAB-1707CQ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: ELISA, IP, FC, FuncS, Neut, IF
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- Species Reactivity: Human
- Type: Human IgG
- Application: FC, ELISA
- Human Anti-FAP Recombinant Antibody (HPAB-0172-CN) (HPAB-0172-CN)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human, Mouse
- Type: Chimeric (mouse/human) IgG1, κ
- Application: ELISA, IHC
- Human Anti-FAP Recombinant Antibody; Fab Fragment (TAB-022WM-F(E)) (TAB-022WM-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: FC, ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC, IF, IP
- Human Anti-FAP Recombinant Antibody (clone cF19) (HPAB-0176-CN)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: ELISA, FC, IHC, IP, IF
- Human Anti-FAP Recombinant Antibody (TAB-022WM) (TAB-022WM)
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: FC, ELISA
- Rabbit Anti-FAP Recombinant Antibody (clone JA56-11) (MRO-0568-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
- Mouse Anti-DR5 Recombinant Antibody (HPAB-0621LY) (HPAB-0621LY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC
- Human Anti-FAP Recombinant Antibody (HPAB-2061-FY) (HPAB-2061-FY)
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- Species Reactivity: Human, Mouse, Cynomolgus monkey
- Type: Human IgG1
- Application: SPR, IHC
- Mouse Anti-DR5 Recombinant Antibody (HPAB-0622LY) (HPAB-0622LY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC
- Human Anti-FAP Recombinant Antibody; scFv Fragment (TAB-022WM-S(P)) (TAB-022WM-S(P))
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: FC, ELISA
- Human Anti-DR5 Recombinant Antibody (clone mAb2) (HPAB-0729LY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Human Anti-DR5 Recombinant Antibody (clone mAb1) (HPAB-0728LY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Human Anti-FAP Recombinant Antibody (clone 34) (HPAB-A1373-YJ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, IHC, FC, Inhib
- PE-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer (MHC-CN0661)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: PE
- APC-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer (MHC-CN0662)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: APC
- FITC-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer (MHC-CN0663)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: FITC
- H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer (MHC-CN0664)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: Unconjugated
- PE-A*02:01/Human FAP (GLFKCGIAV) MHC Tetramer (MHC-CN0665)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: PE
- APC-A*02:01/Human FAP (GLFKCGIAV) MHC Tetramer (MHC-CN0666)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: APC
- FITC-A*02:01/Human FAP (GLFKCGIAV) MHC Tetramer (MHC-CN0667)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: FITC
- A*02:01/Human FAP (GLFKCGIAV) MHC Tetramer (MHC-CN0668)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: Unconjugated
- PE-A*02:01/Human FAP (ALVCYGPGI) MHC Tetramer (MHC-CN0669)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: PE
- APC-A*02:01/Human FAP (ALVCYGPGI) MHC Tetramer (MHC-CN0670)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: APC
- Mouse Anti-DR5 Recombinant Antibody; Fab Fragment (HPAB-0622LY-F(E)) (HPAB-0622LY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC
- Human Anti-DR5 Recombinant Antibody (clone mAb1); Fab Fragment (HPAB-0728LY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-DR5 Recombinant Antibody (clone mAb2); Fab Fragment (HPAB-0729LY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL13
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: IgG-IL13
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL13
- Host: Human
- Cytokine 1 Species: Mouse
- Molecule Class: IgG-IL13
- Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0668-YJ-F(E)) (HPAB-0668-YJ-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, Inhib, IHC, IF, FuncS
- Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0668-YJ-S(P)) (HPAB-0668-YJ-S(P))
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: ELISA, Inhib, IHC, IF, FuncS
- Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-2061-FY-S(P)) (HPAB-2061-FY-S(P))
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- Species Reactivity: Human, Mouse, Cynomolgus monkey
- Type: Human scFv
- Application: FC, ELISA, IF
- Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-2061-FY-F(E)) (HPAB-2061-FY-F(E))
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- Species Reactivity: Human, Mouse, Cynomolgus monkey
- Type: Human Fab
- Application: FC, ELISA, IF
- Human Anti-DR5 Recombinant Antibody (clone mAb2); scFv Fragment (HPAB-0729LY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC, ELISA
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- Species Reactivity: Human
- Type: Human scFv
- Application: FC, ELISA
- Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0173-CN-F(E)) (HPAB-0173-CN-F(E))
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: ELISA
- Human Anti-DR5 Recombinant Antibody (clone mAb1); scFv Fragment (HPAB-0728LY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Anti-FAP Antibody-Cytokine Fusion Protein, FAB-IL10 (ACFP-SH009)
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL10
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: Fab-IL10
- Human Anti-FAP Recombinant Antibody (clone ESC14); Fab Fragment (HPAB-0175-CN-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, WB, FC, IHC, IP
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL10
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: IgG1-IL10
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL10
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: Fab-IL10
- Mouse Anti-FAP Recombinant Antibody (clone cF19); scFv Fragment (HPAB-0176-CN-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC, IHC, IP, IF
- Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0170-CN-F(E)) (HPAB-0170-CN-F(E))
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, IF
- Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0170-CN-S(P)) (HPAB-0170-CN-S(P))
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: ELISA, IF
- Anti-FAP Antibody-Cytokine Fusion Protein, IgG-IL10 (ACFP-SH008)
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL10
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: IgG1-IL10
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- Derivation: VHH phage display library
- Species Reactivity: Human
- Type: VHH
- Application: ELISA
- Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0172-CN-F(E)) (HPAB-0172-CN-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human, Mouse
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, IHC
- Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0173-CN-S(P)) (HPAB-0173-CN-S(P))
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized scFv
- Application: ELISA
- Human Anti-FAP Recombinant Antibody (clone ESC14); scFv Fragment (HPAB-0175-CN-S(P))
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: ELISA, WB, FC, IHC, IP
- Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-2062-FY-S(P)) (HPAB-2062-FY-S(P))
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: FC, ELISA, IF
- Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-2062-FY-F(E)) (HPAB-2062-FY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: FC, ELISA, IF
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL12
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: scfv-IL12
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL12
- Host: Human
- Cytokine 1 Species: Mouse
- Molecule Class: scfv-IL12
- Mouse Anti-DR5 Recombinant Antibody; Fab Fragment (HPAB-0621LY-F(E)) (HPAB-0621LY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC
- Mouse Anti-DR5 Recombinant Antibody; scFv Fragment (HPAB-0622LY-S(P)) (HPAB-0622LY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC
- Mouse Anti-DR5 Recombinant Antibody; scFv Fragment (HPAB-0621LY-S(P)) (HPAB-0621LY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC
- Mouse Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0171-CN-S(P)) (HPAB-0171-CN-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Classification: Fc glycosylation/Non fucosylated
- Glycosylation site: Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Classification: Fc glycosylation/Non fucosylated
- Glycosylation site: Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Classification: Fc glycosylation/Non fucosylated
- Glycosylation site: Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Classification: Fc glycosylation/Non fucosylated
- Glycosylation site: Fc region
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Human IgG1 kappa
- Application: ELISA, IP, FC Neut, IF, WB
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Classification: Fc glycosylation/Non fucosylated
- Glycosylation site: Fc region
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- Species Reactivity: Human
- Type: Mouse IgG1 kappa
- Application: Antigen-Sweeping In Vivo.
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- Targets: DR5 & FAP
- Type: Fab2
- Application: FuncS, Promising therapeutic agent
- Anti-FAP (G11)-AO-MC-MMAE ADC (ADC-098LCT)
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- Target: FAP
- Linker: AO-Mc-
- Drug: MMAE (Monomethyl auristatin E)
- Anti-fibroblast activation proteinα-SMCC-DM1 ADC (ADC-161LZY)
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- Target: fibroblast activation proteinα
- Linker: SMCC (4-[N-maleimidomethyl] cyclohexane-1 carboxylhydrazide).
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-FAP-AO-MMAE (Glyco MMAE) ADC (ADC-100LCT)
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- Target: FAP
- Linker: AO-Mc-
- Drug: MMAE (Monomethyl auristatin E)
- Anti-FAP-MC-VC-PAB-MMAE ADC (ADC-099LCT)
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- Target: FAP
- Linker: MC-PABC (maleimidocaproyl-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Human Anti-FAP (clone cF19) scFv-Fc Chimera (VS-0325-FY118)
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- Species Reactivity: Human
- Type: Human IgG1, scFv-Fc
- Application: FC, IHC, IP
- Anti-FAP Immunohistochemistry Kit (VS-0325-XY813)
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- Species Reactivity: Human, Mouse, Rat
- Target: FAP
- Application: IHC
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC-P, FC, ELISA
- Anti-Human FAP Immunohistochemistry Kit (VS-0525-XY2444)
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- Species Reactivity: Human
- Target: FAP
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
DR5 is a member of the TNF receptor superfamily that can induce apoptosis upon binding to TRAIL.
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.


