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DR5 & FAP
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Recombinant Antibody Products
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Formats
Anti-DR5 & FAP Recombinant Antibody Products
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, IP, FC, FuncS, Neut, IF, WB
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- Human Anti-FAP Recombinant Antibody (TAB-024WM) (TAB-024WM)
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- Species Reactivity: Human, Mouse, Monkey
- Type: Human IgG1
- Application: IHC, ELISA, FC, IF
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- Human Anti-FAP Recombinant Antibody (clone ESC14) (HPAB-0175-CN)
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: ELISA, WB, FC, IHC, IP
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- Mouse Anti-FAP Recombinant Antibody (HPAB-0171-CN) (HPAB-0171-CN)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG2a
- Application: ELISA
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- Mouse Anti-FAP Recombinant Antibody (clone F19) (HPAB-A1368-YJ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FuncS, RIA, IP, IF, IHC, IA, Block
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- Human Anti-FAP Recombinant Antibody (clone cF19); Fab Fragment (HPAB-0176-CN-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, FC, IHC, IP, IF
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- Human Anti-FAP Recombinant Antibody (HPAB-0668-YJ) (HPAB-0668-YJ)
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: ELISA, Inhib, IHC, IF, FuncS
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- Human Anti-FAP Recombinant Antibody; Fab Fragment (TAB-024WM-F(E)) (TAB-024WM-F(E))
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- Species Reactivity: Human, Mouse, Monkey
- Type: Human Fab
- Application: ELISA, FC, IF
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- Mouse Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0171-CN-F(E)) (HPAB-0171-CN-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA
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- Human Anti-DR5 Recombinant Antibody (clone YC037) (MOB-0245MC)
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- Species Reactivity: Human
- Application: ELISA, WB, IHC, FuncS
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- Mouse Anti-DR5 Recombinant Antibody (HPAB-0621LY) (HPAB-0621LY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC
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- Mouse Anti-DR5 Recombinant Antibody (HPAB-0622LY) (HPAB-0622LY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC
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- Human Anti-DR5 Recombinant Antibody (clone mAb1) (HPAB-0728LY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Human Anti-DR5 Recombinant Antibody (clone mAb2) (HPAB-0729LY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Human Anti-FAP Recombinant Antibody; scFv Fragment (TAB-022WM-S(P)) (TAB-022WM-S(P))
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: FC, ELISA
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- Human Anti-FAP Recombinant Antibody; scFv Fragment (TAB-024WM-S(P)) (TAB-024WM-S(P))
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- Species Reactivity: Human, Mouse, Monkey
- Type: Human scFv
- Application: ELISA, FC, IF
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- Human Anti-FAP Recombinant Antibody; Fab Fragment (TAB-022WM-F(E)) (TAB-022WM-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: FC, ELISA
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- Human Anti-DR5 Recombinant Antibody (clone KMTR1) (FAMAB-1693CQ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: RIA, FuncS, ELISA
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- Human Anti-DR5 Recombinant Antibody (clone DR5TAA-0005) (FAMAB-1707CQ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA
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- Human Anti-DR5 Recombinant Antibody (clone 304) (FAMAB-1708CQ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: RIA, FuncS, ELISA
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- Human Anti-DR5 Antibody (clone KMTR1), mRNA (FAMAB-1693CQ-mRNA)
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- Species Reactivity: Human
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- Human Anti-DR5 Antibody (clone DR5TAA-0005), mRNA (FAMAB-1707CQ-mRNA)
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- Species Reactivity: Human
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- Human Anti-FAP Recombinant Antibody (TAB-022WM) (TAB-022WM)
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: FC, ELISA
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- Recombinant Mouse Anti-Human FAP Antibody (MOB-1515MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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- Human Anti-FAP Recombinant Antibody (HPAB-0170-CN) (HPAB-0170-CN)
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human IgG
- Application: ELISA, IF
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- Rabbit Anti-FAP Recombinant Antibody (clone JA56-11) (MRO-0568-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
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- Rabbit Anti-FAP Polyclonal Antibody (MRO-1853-CN) (MRO-1853-CN)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, FC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: ELISA, IP, FC, FuncS, Neut, IF
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- PE-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer (MHC-CN0661)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: PE
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- APC-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer (MHC-CN0662)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: APC
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- FITC-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer (MHC-CN0663)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: FITC
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- H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer (MHC-CN0664)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: Unconjugated
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- PE-A*02:01/Human FAP (GLFKCGIAV) MHC Tetramer (MHC-CN0665)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: PE
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- APC-A*02:01/Human FAP (GLFKCGIAV) MHC Tetramer (MHC-CN0666)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: APC
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- FITC-A*02:01/Human FAP (GLFKCGIAV) MHC Tetramer (MHC-CN0667)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: FITC
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- A*02:01/Human FAP (GLFKCGIAV) MHC Tetramer (MHC-CN0668)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: Unconjugated
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- PE-A*02:01/Human FAP (ALVCYGPGI) MHC Tetramer (MHC-CN0669)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: PE
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- APC-A*02:01/Human FAP (ALVCYGPGI) MHC Tetramer (MHC-CN0670)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: APC
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- FITC-A*02:01/Human FAP (ALVCYGPGI) MHC Tetramer (MHC-CN0671)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: FITC
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- A*02:01/Human FAP (ALVCYGPGI) MHC Tetramer (MHC-CN0672)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: Unconjugated
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- Human Anti-FAP Recombinant Antibody (HPAB-0172-CN) (HPAB-0172-CN)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human, Mouse
- Type: Chimeric (mouse/human) IgG1, κ
- Application: ELISA, IHC
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- Human Anti-FAP Recombinant Antibody (clone cF19) (HPAB-0176-CN)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: ELISA, FC, IHC, IP, IF
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- Human Anti-FAP Recombinant Antibody (HPAB-2062-FY) (HPAB-2062-FY)
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: FC
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- Human Anti-FAP Recombinant Antibody (HPAB-0173-CN) (HPAB-0173-CN)
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized IgG1, κ
- Application: ELISA
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- A*02:01/Human FAP (GLFKCGIAV) MHC Pentamer (MHC-YF431)
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- A*02:01/Human FAP alpha (ALVCYGPGI) MHC Pentamer (MHC-YF432)
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- Class: Class I
- Antigen: FAP alpha
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- H-2Kb/Human muFAP alpha (SDYYFSWL) MHC Pentamer (MHC-YF573)
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- Class: Class I
- Antigen: muFAP alpha
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- Human Anti-FAP Recombinant Antibody (HPAB-2061-FY) (HPAB-2061-FY)
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- Species Reactivity: Human, Mouse, Cynomolgus monkey
- Type: Human IgG1
- Application: SPR, IHC
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- Human Anti-FAP Recombinant Antibody (clone 34) (HPAB-A1373-YJ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, IHC, FC, Inhib
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- Human Anti-FAP Recombinant Antibody (clone 18) (HPAB-A1374-YJ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, FC, Inhib
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- Rabbit Anti-FAP Recombinant Antibody (VS-0723-WK245) (VS-0723-WK245)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, FC
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL12
- Host: Human
- Cytokine 1 Species: Mouse
- Molecule Class: scfv-IL12
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL12
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: scfv-IL12
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL13
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: IgG-IL13
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL13
- Host: Human
- Cytokine 1 Species: Mouse
- Molecule Class: IgG-IL13
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- Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-2061-FY-F(E)) (HPAB-2061-FY-F(E))
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- Species Reactivity: Human, Mouse, Cynomolgus monkey
- Type: Human Fab
- Application: FC, ELISA, IF
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- Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-2061-FY-S(P)) (HPAB-2061-FY-S(P))
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- Species Reactivity: Human, Mouse, Cynomolgus monkey
- Type: Human scFv
- Application: FC, ELISA, IF
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- Derivation: VHH phage display library
- Species Reactivity: Human
- Type: VHH
- Application: ELISA
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- Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-2062-FY-F(E)) (HPAB-2062-FY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: FC, ELISA, IF
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- Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-2062-FY-S(P)) (HPAB-2062-FY-S(P))
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: FC, ELISA, IF
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- Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0668-YJ-F(E)) (HPAB-0668-YJ-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, Inhib, IHC, IF, FuncS
Compare
- Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0668-YJ-S(P)) (HPAB-0668-YJ-S(P))
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: ELISA, Inhib, IHC, IF, FuncS
Compare
- Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0170-CN-S(P)) (HPAB-0170-CN-S(P))
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: ELISA, IF
Compare
- Mouse Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0171-CN-S(P)) (HPAB-0171-CN-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA
Compare
- Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0173-CN-S(P)) (HPAB-0173-CN-S(P))
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized scFv
- Application: ELISA
Compare
- Human Anti-FAP Recombinant Antibody (clone ESC14); scFv Fragment (HPAB-0175-CN-S(P))
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: ELISA, WB, FC, IHC, IP
Compare
- Mouse Anti-FAP Recombinant Antibody (clone cF19); scFv Fragment (HPAB-0176-CN-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC, IHC, IP, IF
Compare
- Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0170-CN-F(E)) (HPAB-0170-CN-F(E))
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, IF
Compare
- Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0173-CN-F(E)) (HPAB-0173-CN-F(E))
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: ELISA
Compare
- Human Anti-FAP Recombinant Antibody (clone ESC14); Fab Fragment (HPAB-0175-CN-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, WB, FC, IHC, IP
Compare
- Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0172-CN-F(E)) (HPAB-0172-CN-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human, Mouse
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, IHC
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- Anti-FAP Antibody-Cytokine Fusion Protein, IgG-IL10 (ACFP-SH008)
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL10
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: IgG1-IL10
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- Anti-FAP Antibody-Cytokine Fusion Protein, FAB-IL10 (ACFP-SH009)
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL10
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: Fab-IL10
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL10
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: IgG1-IL10
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL10
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: Fab-IL10
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- Mouse Anti-DR5 Recombinant Antibody; Fab Fragment (HPAB-0621LY-F(E)) (HPAB-0621LY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC
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- Mouse Anti-DR5 Recombinant Antibody; Fab Fragment (HPAB-0622LY-F(E)) (HPAB-0622LY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC
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- Human Anti-DR5 Recombinant Antibody (clone mAb1); Fab Fragment (HPAB-0728LY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Human Anti-DR5 Recombinant Antibody (clone mAb2); Fab Fragment (HPAB-0729LY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
Compare
- Mouse Anti-DR5 Recombinant Antibody; scFv Fragment (HPAB-0621LY-S(P)) (HPAB-0621LY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC
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- Mouse Anti-DR5 Recombinant Antibody; scFv Fragment (HPAB-0622LY-S(P)) (HPAB-0622LY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC
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- Human Anti-DR5 Recombinant Antibody (clone mAb1); scFv Fragment (HPAB-0728LY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
Compare
- Human Anti-DR5 Recombinant Antibody (clone mAb2); scFv Fragment (HPAB-0729LY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
Compare
- Anti-FAP (G11)-AO-MC-MMAE ADC (ADC-098LCT)
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- Target: FAP
- Linker: AO-Mc-
- Drug: MMAE (Monomethyl auristatin E)
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- Anti-FAP-MC-VC-PAB-MMAE ADC (ADC-099LCT)
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- Target: FAP
- Linker: MC-PABC (maleimidocaproyl-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
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- Anti-FAP-AO-MMAE (Glyco MMAE) ADC (ADC-100LCT)
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- Target: FAP
- Linker: AO-Mc-
- Drug: MMAE (Monomethyl auristatin E)
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- Anti-fibroblast activation proteinα-SMCC-DM1 ADC (ADC-161LZY)
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- Target: fibroblast activation proteinα
- Linker: SMCC (4-[N-maleimidomethyl] cyclohexane-1 carboxylhydrazide).
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
Compare
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.