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DRD5

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For Research Use Only. Not For Clinical Use.


This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2.
Protein class

Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Horizontal cells, Excitatory neurons)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Not detected

Molecular function

G-protein coupled receptor, Receptor, Transducer

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