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E. coli Stx2A
Loading...Anti-E. coli Stx2A Products
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- Derivation: Mouse
- Species Reactivity: E. coli
- Type: ADCC enhanced antibody
- Application: ELISA, FC, IP, FuncS, IF, Neut
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- Mouse Anti-E. coli Stx2A Antibody, mRNA (TAB-H61-mRNA) (TAB-H61-mRNA)
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- Species Reactivity: E. coli
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- Recombinant Anti-E. coli Stx2A VHH Single Domain Antibody (NAB-2306-sdAb)
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- Species Reactivity: E. coli
- Type: Llama VHH
- Application: Neut, ChiP, IP, FUNC
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For Research Use Only. Not For Clinical Use.
Background
Stx2A refers to the A subunit of Shiga toxin 2, produced by Escherichia coli. This subunit is the enzymatic portion of the toxin. After the holotoxin is bound to a cells surface through the Stx2B subunit, the A subunit is internalized. Once inside the cell it inhibits protein synthesis by modifying the 28S rRNA. Stx2 is generally considered more potent then Stx1, and is heavily linked to severe cases of hemolytic uremic syndrome.
