Transcription factors
Intracellular
Cell type enhanced (Erythroid cells, Gastric mucus-secreting cells, Squamous epithelial cells, Plasma cells)
Not detected in immune cells
Low cell line specificity
Homodimer and heterodimer: mainly forms homodimers and, to a lesser extent, heterodimers with E2F8. Dimerization is important for DNA-binding. Interacts with HIF1A.
Activator, DNA-binding, Repressor
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For Research Use Only. Not For Clinical Use.