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EIF4EBP3

Anti-EIF4EBP3 Products
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- Species Reactivity: Human
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the EIF4EBP family, which consists of proteins that bind to eukaryotic translation initiation factor 4E and regulate its assembly into EIF4F, the multi-subunit translation initiation factor that recognizes the mRNA cap structure. Read-through transcription from the neighboring upstream gene (MASK or ANKHD1) generates a transcript (MASK-BP3) that encodes a protein comprised of the MASK protein sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments. [provided by RefSeq, Oct 2010]
Protein class
Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Basal squamous epithelial cells, Proximal enterocytes, Squamous epithelial cells, Exocrine glandular cells, Gastric mucus-secreting cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HHSteC, JURKAT, Karpas-707)
Interaction
EIF4EBP3 interacts with EIF4E.
Molecular function
Protein synthesis inhibitor
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