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EME1
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- Anti-EME1 Immunohistochemistry Kit (VS-0525-XY2271)
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- Species Reactivity: Human
- Target: EME1
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Spermatocytes, Spermatogonia, Extravillous trophoblasts, Cytotrophoblasts, Granulosa cells)
Immune cell specificity
Immune cell enriched (basophil)
Cell line specificity
Low cell line specificity
Interaction
May self-associate. Interacts with MUS81.
Molecular function
Endonuclease, Hydrolase, Nuclease
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