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EOMES

Anti-EOMES Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB, IP, ELISA
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG1, kappa
- Application: FC
- Anti-EOMES Immunohistochemistry Kit (VS-0525-XY2301)
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- Species Reactivity: Human
- Target: EOMES
- Application: IHC
- Anti-Mouse EOMES Immunohistochemistry Kit (VS-0525-XY2302)
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- Species Reactivity: Human, Mouse, Rat
- Target: EOMES
- Application: IHC
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For Research Use Only. Not For Clinical Use.
EOMES encodes a transcription factor involved in the differentiation of specific cell types, particularly in the development of T cells and other immune cells. EOMES is part of the T-box family of transcription factors and is critical for the development of the mesoderm and endoderm during early embryogenesis. In the immune system, EOMES influences the differentiation of cytotoxic T lymphocytes and natural killer (NK) cells. Its role in immune function has been linked to both adaptive and innate immunity. Additionally, EOMES expression is critical in regulating the immune response in infections and cancer.
Protein class
Disease related genes, Human disease related genes, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (NK-cells, dendritic cells, T-cells, Erythroid cells)
Immune cell specificity
Group enriched (NK-cell, MAIT T-cell, memory CD8 T-cell, gdT-cell, naive CD8 T-cell)
Cell line specificity
Cell line enhanced (HDLM-2, JURKAT, SCLC-21H)
Molecular function
Activator, Developmental protein, DNA-binding
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