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EPS15L1

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For Research Use Only. Not For Clinical Use.


EPS15L1 (Epidermal Growth Factor Receptor Pathway Substrate 15 Like 1) is a Protein Coding gene. Diseases associated with EPS15L1 include Split Hand-Split Foot Malformation and Split Foot. Among its related pathways are Listeria monocytogenes entry into host cells and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is EPS15.
Protein class

Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) (By similarity). Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2. Interacts with UBQLN1 (via ubiquitin-like domain). Interacts with CAVIN3 (via leucine-zipper domain) (PubMed:19262564). Interacts with REPS2 (PubMed:10393179).

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