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F protein

Anti-F protein Products
- Human Anti-F Protein Recombinant Antibody (HPAB-AP088-YC) (HPAB-AP088-YC)
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- Species Reactivity: RSV, MPV
- Type: Human IgG1
- Application: ELISA, FC, Neut
- Human Anti-F Protein Recombinant Antibody (HPAB-AP089-YC) (HPAB-AP089-YC)
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- Species Reactivity: RSV, MPV
- Type: Human IgG1
- Application: ELISA, FC, Neut
- Human Anti-F Protein Antibody, mRNA (Gly-020LC-mRNA)
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- Species Reactivity: Human
- Human Anti-F Protein Recombinant Antibody; scFv Fragment (HPAB-AP088-YC-S(P)) (HPAB-AP088-YC-S(P))
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- Species Reactivity: RSV, MPV
- Type: Human scFv
- Application: ELISA, FC, Neut
- Human Anti-F Protein Recombinant Antibody; scFv Fragment (HPAB-AP089-YC-S(P)) (HPAB-AP089-YC-S(P))
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- Species Reactivity: RSV, MPV
- Type: Human scFv
- Application: ELISA, FC, Neut
- Human Anti-F Protein Recombinant Antibody; Fab Fragment (HPAB-AP088-YC-F(E)) (HPAB-AP088-YC-F(E))
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- Species Reactivity: RSV, MPV
- Type: Human Fab
- Application: ELISA, FC, Neut
- Human Anti-F Protein Recombinant Antibody; Fab Fragment (HPAB-AP089-YC-F(E)) (HPAB-AP089-YC-F(E))
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- Species Reactivity: RSV, MPV
- Type: Human Fab
- Application: ELISA, FC, Neut
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: CDR2 of VH
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For Research Use Only. Not For Clinical Use.
Background
The henipavirus Fusion glycoprotein is synthesized as a precursor F₀ that undergoes posttranslational cleavage by host cell Cathepsin L that occurs within the endosomal compartment, most likely during endocytosis and recycling of F to the mature fusiogenic F₁ (a larger carboxy terminal fragment) +F₂ (a smaller amino terminal fragment) subunits that are held together by disulfide bonds through conserved cystine residues.