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FATE1
Loading...Anti-FATE1 Products
- Mouse Anti-NHP FATE1 Recombinant Antibody (clone OTI6F10) (VS-1024-XY200)
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- Species Reactivity: Dog, Human, Mouse, Non-human primate, Rat
- Type: Mouse IgG1
- Application: WB, IF
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- Anti-FATE1 Immunohistochemistry Kit (VS-0525-XY2454)
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- Species Reactivity: Human
- Target: FATE1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a cancer-testis antigen that is highly expressed in hepatocellular carcinomas and other tumors and weakly expressed in normal tissues except testis. The protein is strongly expressed in spermatogonia, primary spermatocytes, and Sertoli cells in seminiferous tubules. This protein may have a role in the control of early testicular differentiation and cell proliferation.
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Late spermatids, Early spermatids, Sertoli cells, Spermatocytes, Theca cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Not detected
Interaction
Interacts with BIK and RNF183 (PubMed:26567849). Interacts with IMMT/MIC60and EMD (PubMed:27402544).
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