Disease related genes, Enzymes, Plasma proteins, Potential drug targets
Membrane
Cell type enhanced (Syncytiotrophoblasts, Theca cells, Granulosa cells, Adipocytes, Distal tubular cells)
Low immune cell specificity
Low cell line specificity
Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBH1) composed of CUL1, SKP1, RBX1 and FBH1 (PubMed:11956208, PubMed:19736316, PubMed:23319600). Interacts with RAD51 (PubMed:23393192). Interacts with RPA2 (PubMed:23319600). Interacts (via PIP-box and RanBP2-type zinc finger) with PCNA (PubMed:23677613).
DNA-binding, Helicase, Hydrolase
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For Research Use Only. Not For Clinical Use.