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FCGR3/FCGR2b

Anti-FCGR3/FCGR2b Products

Rat Anti-FCGR3/FCGR2b Recombinant Antibody (NEUT-792CQ) (NEUT-792CQ)
- Species Reactivity: Mouse
- Type: Rat IgG2
- Application: Block
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Rabbit Anti-FCGR3/FCGR2b Recombinant Antibody (clone 2.4G2) (NEUT-793CQ)
- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: Neut, FC, IHC, IP, CyTOF®, IF
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Rat Anti-FCGR3/FCGR2b Recombinant Antibody (clone YC085) (NEUT-794CQ)
- Species Reactivity: Mouse
- Type: Rat IgG2b, κ
- Application: FC, IF, IP, IHC, Block
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Rat Anti-FCGR3/FCGR2b Recombinant Antibody (clone 93) (NEUT-795CQ)
- Species Reactivity: Mouse
- Type: Rat IgG2b, κ
- Application: ICC, IF, FC, Block
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Rat Anti-FCGR3/FCGR2b Recombinant Antibody (clone YT1.24) (NEUT-796CQ)
- Species Reactivity: Mouse
- Type: Rat IgG1
- Application: IHC-Fr, FC, Block
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For Research Use Only. Not For Clinical Use.

Background

Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of antigen-antibody complexes from the circulation and modulation of antibody production by B-cells. Isoform IIB1 and isoform IIB1' form caps but fail to mediate endocytosis or phagocytosis. Isoform IIB2 can mediate the endocytosis of soluble immune complexes via clathrin-coated pits. Isoform IIB1 and isoform IIB2 can down-regulate B-cell, T-cell, and mast cell activation when coaggregated to B-cell receptors for AG (BCR), T-cell receptors for AG (TCR), and Fc receptors, respectively.