+ Filter
Loading...
FECH
Anti-FECH Recombinant Antibody Products
- Mouse Anti-FECH Recombinant Antibody (clone CBF3) (MOB-114YJL)
-
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, IHC-P, ELISA
Compare
More Infomation
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
Catalyzes the ferrous insertion into protoporphyrin IX
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Group enriched (Erythroid cells, Distal tubular cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HMC-1, K-562, U-266/70)
Interaction
Homodimer (PubMed:17261801, PubMed:30765471). Interacts with PGRMC1; the interaction results in decreased FECH activity (PubMed:27599036). Interacts with ABCB10 and SLC25A37; this interaction forms an oligomeric complex (By similarity). Forms a complex with ABCB7 and ABCB10, where a dimeric FECH bridges ABCB7 and ABCB10 homodimers; this complex may be required for cellular iron homeostasis, mitochondrial function and heme biosynthesis (PubMed:30765471). Interacts with ABCB7 and ABCB10 (PubMed:30765471).
Molecular function
Lyase
More Types Infomation