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FNTA
Loading...Anti-FNTA Products
- Anti-FNTA Immunohistochemistry Kit (VS-0525-XY2600)
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- Species Reactivity: Human
- Target: FNTA
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13.
Protein class
Enzymes, FDA approved drug targets, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with MUSK; the interaction is direct and mediates AGRIN-induced phosphorylation of FNTA (By similarity). Heterodimer of FNTA and FNTB (farnesyltransferase). Heterodimer of FNTA and PGGT1B (geranylgeranyltransferase).
Molecular function
Prenyltransferase, Transferase
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