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FOXF2

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For Research Use Only. Not For Clinical Use.


Background

FOXF2 encodes forkhead box F2, one of many human homologues of the Drosophila melanogaster transcription factor forkhead. FOXF2 is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes.
Protein class

Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Microglial cells, Fibroblasts, Smooth muscle cells, Endothelial cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (BJ hTERT+, HEK93, U-2197)

Interaction

Interacts with the transcription factors TBP and TFIIB.

Molecular function

Activator, DNA-binding

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