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FTCD

Anti-FTCD Products

Rabbit Anti-FTCD Recombinant Antibody (clone JF099-5) (MRO-0010-CN)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC, FC
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AbPlus™ Anti-FTCD Magnetic Beads (VS-0724-YC161) (VS-0724-YC161)
- Target: FTCD
- Target Species: Human
- Application: IP, Protein Purification
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Mouse Anti-FTCD Recombinant Antibody (clone 41A7) (MOB-2627z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ICC, IF, IHC
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Recombinant Mouse anti-Human FTCD Monoclonal antibody (EML1139) (MOB-1157CT)
- Species Reactivity: Human
- Application: IHC-P, WB
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Hi-Affi™ Rabbit Anti-FTCD Recombinant Antibody (clone DS1357AB) (MOR-1357)
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
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Anti-FTCD Immunohistochemistry Kit (VS-0325-XY867)
- Species Reactivity: Human, Rat
- Target: FTCD
- Application: IHC
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Anti-Mouse FTCD Immunohistochemistry Kit (VS-0525-XY2659)
- Species Reactivity: Human, Mouse, Rat, Bovine, Canine, Chicken, Hamster
- Target: FTCD
- Application: IHC
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For Research Use Only. Not For Clinical Use.

The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Dec 2009]

Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Hepatocytes, Proximal tubular cells, Cholangiocytes, Late spermatids, Early spermatids)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (Hep G2)

Interaction

Homooctamer, including four polyglutamate binding sites. The subunits are arranged as a tetramer of dimers, and form a planar ring-shaped structure.

Molecular function

Lyase, Multifunctional enzyme, Transferase

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