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Anti-FcRn Recombinant Antibody Products

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Anti-FcRn Products

    • Species Reactivity: (At both a pH of 6.0 and a pH of 7.4) Cross-react with mouse FcRn
      (At both a pH of 6.0 and a pH of 7.4) Cross-react with rat FcRn
      (At both a pH of 6.0 and a pH of 7.4) Cross-react with monkey FcRn
    • Type: Human Fab
    • Application: ELISA, FC, Block, SPR
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    • Species Reactivity: (At both a pH of 6.0 and a pH of 7.4) Cross-react with mouse FcRn
      (At both a pH of 6.0 and a pH of 7.4) Cross-react with rat FcRn
      (At both a pH of 6.0 and a pH of 7.4) Cross-react with monkey FcRn
    • Type: Human IgG
    • Application: ELISA, FC, Block, SPR
    Go to compare Compare
    • Species Reactivity: (At both a pH of 6.0 and a pH of 7.4) Cross-react with mouse FcRn
      (At both a pH of 6.0 and a pH of 7.4) Cross-react with rat FcRn
      (At both a pH of 6.0 and a pH of 7.4) Cross-react with monkey FcRn
    • Type: Human Fab
    • Application: ELISA, FC, Block, SPR
    Go to compare Compare
    • Species Reactivity: (At both a pH of 6.0 and a pH of 7.4) Cross-react with mouse FcRn
      (At both a pH of 6.0 and a pH of 7.4) Cross-react with rat FcRn
      (At both a pH of 6.0 and a pH of 7.4) Cross-react with monkey FcRn
    • Type: Human scFv
    • Application: ELISA, FC, Block, SPR
    Go to compare Compare
    • Species Reactivity: (At both a pH of 6.0 and a pH of 7.4) Cross-react with mouse FcRn
      (At both a pH of 6.0 and a pH of 7.4) Cross-react with rat FcRn
      (At both a pH of 6.0 and a pH of 7.4) Cross-react with monkey FcRn
    • Type: Human scFv
    • Application: ELISA, FC, Block, SPR
    Go to compare Compare
    • Species Reactivity: (At both a pH of 6.0 and a pH of 7.4) Cross-react with mouse FcRn
      (At both a pH of 6.0 and a pH of 7.4) Cross-react with rat FcRn
      (At both a pH of 6.0 and a pH of 7.4) Cross-react with monkey FcRn
    • Type: Human IgG
    • Application: ELISA, FC, Block, SPR
    Go to compare Compare
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For Research Use Only. Not For Clinical Use.


Creative Biolabs offers a comprehensive range of high-quality anti-FcRn recombinant antibodies. These antibodies are engineered with precision and deliver exceptional specificity and affinity, making them ideal for diverse immunological research. Our industrial-leading production approaches guarantee optimal performance and reliability, supporting your scientific pursuits. Whether you're investigating FcRn's role in immune function or developing targeted therapies, our anti-FcRn antibodies provide the essential tools for your success.

FcRn: A Potential Target for Cancer Treatment

FcRn, a heterodimeric MHC class I molecule composed of FCGRT and β2m, plays a critical role in the binding, transport, and recycling of IgG and albumin, thereby protecting them from degradation. While this function is essential for maintaining immune homeostasis, aberrant FcRn activity has been implicated in cancer progression. Specifically, dysregulated FcRn-mediated albumin uptake can contribute to metabolic reprogramming and tumor growth. Consequently, targeting FcRn represents a promising therapeutic strategy for cancer treatment.

Alternative Names

Neonatal fragment crystallizable receptor; IgG receptor FcRn large subunit p51; Brambell receptor; The neonatal Fc receptor for IgG; IgG Fc receptor; Fc receptor FcRn.

Background

This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants.

Anti-FcRn Recombinant Antibody Products

Creative Biolabs offers a comprehensive portfolio of anti-FcRn recombinant antibodies meticulously engineered for precise FcRn targeting and neutralization. These antibodies are available in multiple formats to accommodate diverse research requirements and exhibit exceptional specificity and affinity. As invaluable tools for advancing scientific investigations, our anti-FcRn antibodies are designed to support your research endeavors with precision and reliability.

Table 1. Featured anti-FcRn recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
TAB-0141CL-F(E) Human Anti-FCRN Recombinant Antibody; Fab Fragment Human Human Fab ELISA, FC, Block, SPR
TAB-0151CL-F(E) Human Anti-FCRN Recombinant Antibody; Fab Fragment Human Human Fab ELISA, FC, Block, SPR
TAB-0145CL-F(E) Human Anti-FCRN Recombinant Antibody; Fab Fragment Human Human Fab ELISA, FC, Block, SPR
TAB-0151CL Human Anti-FCRN Recombinant Antibody Human Human IgG ELISA, FC, Block, SPR
TAB-274CL Human Anti-FCRN Recombinant Antibody Human Human IgG ELISA

Creative Quality Control

Creative Biolabs is dedicated to delivering premium anti-FcRn recombinant antibodies designed to meet the rigorous demands of scientific research. Our seasoned professionals, alongside our sophisticated facilities and robust quality control systems, ensure that our antibodies display excellent specificity and binding affinity. By partnering with Creative Biolabs, you can confidently rely on our products to enhance the precision and success of your research endeavors.

Fig.1 WB analysis. (Creative Biolabs Original)Fig.1 WB analysis of anti-FcRn antibody
(Cat# TAB-0145CL-F(E), Creative Biolabs).

Fig.2 ELISA analysis. (Creative Biolabs Original)Fig.2 ELISA analysis of anti-FcRn antibody
(Cat# TAB-0145CL-F(E), Creative Biolabs).

Fig.3 DB analysis. (Creative Biolabs Original)Fig.3 DB analysis of anti-FcRn antibody
(Cat# TAB-0145CL-F(E), Creative Biolabs).

Customer Reviews

Excellent
Je***y
Human Anti-FCRN Recombinant Antibody (TAB-0146CL) (TAB-0146CL)
I've been studying the function of the Fc receptor in neonates using anti-FcRn antibodies from Creative Biolabs. The antibodies have exhibited exceptional specificity and affinity on many occasions, enabling me to precisely identify and measure FcRn in diverse biological specimens. I'm pleased with these antibodies’ performance and quality.
15/Oct/2021
Excellent
Ky***l
Human Anti-FCRN Recombinant Antibody (TAB-274CL) (TAB-274CL)
Creative Biolabs' anti-FcRn antibodies have proven to be highly robust and reliable in my ELISA assays. They have consistently performed well across multiple experimental conditions, providing me with consistent and reproducible results. The reliability of these antibodies has been crucial for ensuring the accuracy and validity of my research findings.
27/Sep/2023
Excellent
An***a
Human Anti-FCRN Recombinant Antibody (TAB-0151CL) (TAB-0151CL)
I've found Creative Biolabs' anti-FcRn antibodies to be extremely versatile. I've successfully used them for ELISA, FC, and Block, and they've performed exceptionally well in each application. The antibodies have helped me gain valuable insights into FcRn expression and function in my research.
26/May/2024

Anti-FcRn Recombinant Antibody Production

Creative Biolabs generates anti-FcRn recombinant antibodies by applying cutting-edge recombinant antibody manufacturing systems. Our innovative genetic engineering technique provides the dependability and flexibility of antibody manufacturing to fulfill our customer's diverse research objectives.

Featured Anti-FcRn Recombinant Antibody Production Platforms Fig.4 Milligram-scale. (Creative Biolabs Original)
Fig.4 Milligram-scale anti-FcRn recombinant antibody production.

Fig.5 Gram-scale. (Creative Biolabs Original)Fig.5 Gram-scale anti-FcRn recombinant antibody production.

Anti-FcRn Recombinant Antibody Modalities

Creative Biolabs offers exceptional anti-FcRn recombinant antibodies in a range of forms to fulfill the diverse demands of our customers.

Fig.6 FcRn antibody production and modalities. (Creative Biolabs Original)Fig.6 Full-length anti-FcRn recombinant antibody production and modalities.

FcRn-Targeted Drug Information

Public Drug Information Targeting FcRn

Table 2. Public drug targeting FcRn.

Company Research Phase Classification Condition
argenx Approved, Phase III Protein Based Therapies
Other protein-based therapies
Myasthenia gravis (adult)
Ucb Inc.
Ucb Pharma S.A.
Approved, Phase III Protein Based Therapies
Monoclonal antibody (mAb)
Generalized myasthenia gravis (gMG) in adult patients
Bioverativ Therapeutics Inc.
SWEDISH ORPHAN BIOVITRUM AB (PUBL)
Sanofi Aventis Deutschland Gmb H
Biogen Inc.
Approved, Phase III Protein Based Therapies
Blood factors
Bleeding caused by hemophilia B (congenital factor IX deficiency)

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

As a market leader in antibody development, Creative Biolabs possesses a competent workforce and cutting-edge technology. We not only deliver high-quality antibodies in a variety of formats but also offer comprehensive support for customers' project progress. If you are seeking an anti-FcRn recombinant antibody product that is appropriate for your significant project, please contact us immediately.

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