Foxp3 / Cd44 / Prdm1 / Il10 / Tgfg
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For Research Use Only. Not For Clinical Use.
Background
These are activated Tregs (often CD44hi, CD62Llow) that have acquired an effector-like phenotype to home to inflamed tissues. They express high levels of suppressive molecules like CTLA-4 and ICOS to control active immune responses locally.