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For Research Use Only. Not For Clinical Use.
Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Part of the core SMN complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8 and STRAP/UNRIP (PubMed:12065586, PubMed:18984161, PubMed:15939020, PubMed:16314521, PubMed:17178713). Part of the SMN-Sm complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8, STRAP/UNRIP and the Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG (PubMed:18984161, PubMed:16314521). Interacts with GEMIN6; the interaction is direct (PubMed:33754639, PubMed:12065586, PubMed:15939020, PubMed:17178713). Interacts with STRAP/UNRIP; the interaction is direct (PubMed:17178713). Interacts with GEMIN8; the interaction is direct (PubMed:33754639). Interacts with SNRPB, SNRPD2, SNRPD3 and SNRPE; the interaction is direct (PubMed:12065586, PubMed:15939020).