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GLMP

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For Research Use Only. Not For Clinical Use.


Background

Involved in protein localization to lysosome and protein stabilization. Located in lysosome and membrane. Is expressed in several structures, including inner ear; liver; lung; metanephros; and spleen. Orthologous to human GLMP (glycosylated lysosomal membrane protein).
Protein class

Transporters

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Hofbauer cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (ASC diff)

Interaction

Interacts (via lumenal domain) with lysosomal protein MFSD1; the interaction starts while both proteins are still in the endoplasmic reticulum and is required for stability and lysosomal localization of MFSD1.

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