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For Research Use Only. Not For Clinical Use.
Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Homotetramere (PubMed:31408337, 30970244). Interacts with MAPK14 (PubMed:16352664). Interacts with KDM1B at nucleosomes; this interaction stimulates H3K4me1 and H3K4me2 demethylation (PubMed:23260659). Binds to mononucleosomes (PubMed:29759984). Interacts with GATA4; the interaction is required for a synergistic activation of GATA4 target genes transcription (PubMed:35182466).
DNA-binding, Oxidoreductase