GMDS

AbPlus Formats

Anti-GMDS Recombinant Antibody Products

Mouse Anti-GMDS Recombinant Antibody (clone 7B1) (MOB-2403z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA, WB
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Anti-GMDS Immunohistochemistry Kit (VS-0325-XY929)
- Species Reactivity: Human, Mouse, Rat
- Target: GMDS
- Application: IHC
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For Research Use Only. Not For Clinical Use.

GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).

Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Intestinal goblet cells, Gastric mucus-secreting cells, Excitatory neurons, Proximal enterocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (OE19)

Molecular function

Lyase

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