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GPVI

Anti-GPVI Products
- Human Anti-GPVI Recombinant Antibody (HPAB-1184WJ) (HPAB-1184WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Inhib, Activ, SPR, FC
- Human Anti-GPVI Recombinant Antibody (HPAB-1185WJ) (HPAB-1185WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Inhib, Activ, SPR, FC
- Human Anti-GPVI Recombinant Antibody (HPAB-2316LY) (HPAB-2316LY)
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- Derivation: Humanized
- Species Reactivity: Human, Monkey
- Type: Humanized IgG
- Application: FC
- Human Anti-GPVI Recombinant Antibody; scFv Fragment (HPAB-2316LY-S(P)) (HPAB-2316LY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human, Monkey
- Type: Human scFv
- Application: FC
- Human Anti-GPVI Recombinant Antibody; Fab Fragment (HPAB-2316LY-F(E)) (HPAB-2316LY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human, Monkey
- Type: Humanized Fab
- Application: FC
- Human Anti-GPVI Recombinant Antibody; scFv Fragment (HPAB-1184WJ-S(P)) (HPAB-1184WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-GPVI Recombinant Antibody; scFv Fragment (HPAB-1185WJ-S(P)) (HPAB-1185WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-GPVI Recombinant Antibody; Fab Fragment (HPAB-1184WJ-F(E)) (HPAB-1184WJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-GPVI Recombinant Antibody; Fab Fragment (HPAB-1185WJ-F(E)) (HPAB-1185WJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.