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GRGDNP
Loading...Anti-GRGDNP Products
- Recombinant Anti-GRGDNP Antibody (MOB-418)
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- Derivation: Mouse
- Type: IgG
- Application: WB, Dot, FuncS
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- Recombinant Human Anti-GRGDNP Antibody (MHH-418)
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- Derivation: Human
- Type: IgG
- Application: WB, IHC, FuncS
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- Recombinant Human Anti-GRGDNP Antibody Fab Fragment (MHH-418-F(E))
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- Derivation: Human
- Type: Fab
- Application: RIA, ELISA, FuncS
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- Recombinant Human Anti-GRGDNP Antibody scFv Fragment (MHH-418-S(P))
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- Derivation: Human
- Type: scFv
- Application: FC, ELISA, FuncS
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- Recombinant Anti-GRGDNP Antibody Fab Fragment (MOB-418-F(E))
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- Derivation: Mouse
- Type: Fab
- Application: ELISA, FacS, FuncS
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- Recombinant Anti-GRGDNP Antibody scFv Fragment (MOB-418-S(P))
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- Derivation: Mouse
- Type: scFv
- Application: Neut, WB, FuncS
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For Research Use Only. Not For Clinical Use.
Background
RGD peptide (GRGDNP) acts as an inhibitor of integrin-ligand interactions and can induce apoptosis in the absence of signals and integrin-mediated cell clustering. Research demonstrates that RGD peptides promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing. The RGD peptide can serve as a cell adhesion site of extracellular matrix, cell surface proteins, and integrins. In addition, RGD peptide can inhibit ACK-2 activation through cell adhesion.