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GRIK5
Loading...Anti-GRIK5 Products
- Mouse Anti-Grik5 Recombinant Antibody (VS-0522-LC191) (VS-0522-LC191)
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- Species Reactivity: Rat, Mouse
- Type: Mouse IgG2a
- Application: ICC, WB, IHC
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- Rat Anti-Grik5 Recombinant Antibody (VS-0522-LC192) (VS-0522-LC192)
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- Species Reactivity: Rat, Mouse
- Type: Rat IgG2b
- Application: ICC, WB, IHC
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- Rabbit Anti-Grik5 Recombinant Antibody (VS-0522-LC193) (VS-0522-LC193)
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- Species Reactivity: Rat, Mouse
- Type: Rabbit IgG
- Application: ICC, WB, IHC
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- SH3 domain scaffold protein anti-Human KA2 (SST-L189)
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- Scaffold Name: SH3 domain
- Target: KA2
- Species Reactivity: Human
- Derivation: Yeast Two-hybrid
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- Mouse Anti-GRIK5 Recombinant Antibody (clone 4G5H8) (VS7-HM1031)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds kainate > quisqualate > domoate > L-glutamate >> AMPA >> NMDA = 1S,3R-ACPD
Protein class
FDA approved drug targets, Transporters
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Excitatory neurons, Oligodendrocyte precursor cells, Inhibitory neurons, Bipolar cells, Rod photoreceptor cells, Horizontal cells, Astrocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HEL, hTERT-RPE1, NTERA-2, REH, SCLC-21H, SH-SY5Y)
Interaction
Tetramer of two or more different subunits. Associates with GRIK1 (both edited and unedited versions), GRIK2, or GRIK3 to form functional channels. Homomeric associations do not produce any channel activity (By similarity).
Molecular function
Ion channel, Ligand-gated ion channel, Receptor
More Types Infomation