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GTF2A1

Anti-GTF2A1 Products

Recombinant Mouse Anti-Human GTF2A1 Antibody (clone 809D5b) (MOB-2459MZ)
- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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Mouse Anti-GTF2A1 Recombinant Antibody (clone 26A5) (MOB-2551z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, ELISA
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For Research Use Only. Not For Clinical Use.

Background

Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Immune cell enhanced (basophil)

Cell line specificity

Low cell line specificity

Interaction

TFIIA is a heterodimer of the large unprocessed subunit 1 and a small subunit gamma. It was originally believed to be a heterotrimer of an alpha (p35), a beta (p19) and a gamma subunit (p12). TFIIA forms a complex with TBP.

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