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GUCA1A

Anti-GUCA1A Products
- Mouse Anti-GUCA1A Recombinant Antibody (VMC181) (NEUT-885CQ)
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- Species Reactivity: Human, Primate, Bovine
- Type: Mouse IgG2a
- Application: Block, IP, WB
- Mouse Anti-NHP GUCA1A Recombinant Antibody (clone G2) (VS-1024-XY216)
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- Species Reactivity: Bovine, Human, Non-human primate
- Type: Mouse IgG2a
- Application: WB
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For Research Use Only. Not For Clinical Use.
This gene encodes an enzyme that plays a role in the recovery of retinal photoreceptors from photobleaching. This enzyme promotes the activity of retinal guanylyl cyclase-1 (GC1) at low calcium concentrations and inhibits GC1 at high calcium concentrations. Mutations in this gene can cause cone dystrophy 3 and code-rod dystrophy 14.

Protein class
Disease related genes, Human disease related genes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Rod photoreceptor cells, Cone photoreceptor cells, Late spermatids, Muller glia cells)
Immune cell specificity
Immune cell enriched (plasmacytoid DC)
Cell line specificity
Group enriched (NTERA-2, SH-SY5Y)
Interaction
Homodimer.
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