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GUCY1B3

Anti-GUCY1B3 Products

Recombinant Mouse Anti-Human GUCY1B3 Antibody (clone C246M) (MOB-0023MZ)
- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA, WB
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Rabbit Anti-GUCY1B3 Recombinant Antibody (clone DS1546AB) (MOR-1546)
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IP, FC
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For Research Use Only. Not For Clinical Use.

Background

This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants.