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GZMH

Anti-GZMH Products

Mouse Anti-GZMH Recombinant Antibody (clone 10G4) (MOB-3440z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2
- Application: WB
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Recombinant Mouse Anti-Human GZMH Antibody (clone NN0420-20B40) (MOB-2291MZ)
- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.

Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3 and P4 sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication.

Protein class

Enzymes

Predicted location

Secreted

Single cell type specificity

Group enriched (dendritic cells, NK-cells, T-cells)

Immune cell specificity

Group enriched (gdT-cell, memory CD8 T-cell, naive CD8 T-cell, memory CD4 T-cell)

Cell line specificity

Cell line enhanced (U-266/70)

Molecular function

Hydrolase, Protease, Serine protease

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