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Ganglioside GD3

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For Research Use Only. Not For Clinical Use.


Background

Ganglioside GD3 is a type of disialoganglioside, a complex glycosphingolipid found primarily in the outer leaflet of the cell plasma membrane, particularly in neural tissues, melanocytes, and some tumor cells.
A ganglioside is a molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids (e.g. n-acetylneuraminic acid, NANA) linked on the sugar chain. NeuNAc, an acetylated derivative of the carbohydrate sialic acid, makes the head groups of gangliosides anionic at pH 7, which distinguishes them from globosides.
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