Gata3 / Il4 / Il5 / Il13
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For Research Use Only. Not For Clinical Use.
Background
Driven by IL-4 signaling and the transcription factor GATA3, Th2 cells are essential for immunity against extracellular parasites (helminths) and help B cells switch to IgE. They secrete type 2 cytokines such as IL-4, IL-5, and IL-13, and are often implicated in allergic responses.