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Gbgt1

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For Research Use Only. Not For Clinical Use.


Background

This gene encodes a glycosyltransferase that plays a role in the synthesis of Forssman glycolipid (FG), a member of the globoseries glycolipid family. Glycolipids such as FG form attachment sites for the binding of pathogens to cells; expression of this protein may determine host tropism to microorganisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Protein class

Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Kupffer cells, Macrophages, Hofbauer cells, Erythroid cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HEL, HMC-1, HUVEC TERT2, NB-4)

Molecular function

Glycosyltransferase, Transferase

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