H1-0
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC
- Anti-Rat H1-0 Immunohistochemistry Kit (VS-0525-XY3005)
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- Species Reactivity: Human, Mouse, Rat
- Target: H1-0
- Application: IHC
- Anti-H1-0 Immunohistochemistry Kit (VS-0525-XY3003)
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- Species Reactivity: Human
- Target: H1-0
- Application: IHC
- Anti-Mouse H1-0 Immunohistochemistry Kit (VS-0525-XY3004)
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- Species Reactivity: Human, Mouse, Rat
- Target: H1-0
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Syncytiotrophoblasts, Extravillous trophoblasts, Hofbauer cells, Cardiomyocytes, Cytotrophoblasts)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (OE19, U-2 OS)
Molecular function
DNA-binding
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