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HADH

Anti-HADH Products
- Mouse Anti-HADH Recombinant Antibody (clone D10-E7) (MRO-0710-CN)
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- Species Reactivity: Human, Mouse, Zebrafish
- Type: Mouse IgG1
- Application: WB, IF, IHC
- Rabbit Anti-HADH Polyclonal Antibody (MRO-1921-CN) (MRO-1921-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC
- AbPlus™ Anti-HADH Magnetic Beads (VS-0724-YC1010) (VS-0724-YC1010)
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- Target: HADH
- Target Species: Human
- Application: IP, Protein Purification
- Recombinant Mouse Anti-Human HADH Antibody (MOB-2297MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: ICC, IF, IHC-P, WB
- Chicken Anti-HADHSC Polyclonal IgY (BRD-0246MZ)
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- Species Reactivity: Human, Mouse, Rat
- Type: Chicken antibody
- Application: IHC
- Chicken Anti-HADH Polyclonal IgY (BRD-1001MZ)
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- Species Reactivity: Human, Mouse, Rat
- Type: Chicken antibody
- Application: WB
- Anti-HADH Immunohistochemistry Kit (VS-0325-XY987)
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- Species Reactivity: Human
- Target: HADH
- Application: IHC
- Anti-Mouse HADH Immunohistochemistry Kit (VS-0525-XY3048)
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- Species Reactivity: Human, Mouse, Rat
- Target: HADH
- Application: IHC
- Anti-Human HADH Immunohistochemistry Kit (VS-0525-XY3047)
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- Species Reactivity: Human
- Target: HADH
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene of this gene on chromosome 15. [provided by RefSeq, May 2010]
Protein class
Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Proximal enterocytes, Proximal tubular cells, Hepatocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homodimer (PubMed:10231530, PubMed:10840044, PubMed:16725361). Interacts with GLUD1; this interaction inhibits the activation of glutamate dehydrogenase 1 (GLUD1) (By similarity).
Molecular function
Oxidoreductase, Transferase
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