HEV ORF2

The Hepatitis E virus, or HEV, is the causative agent of Hepatitis E. Its taxonomic name is Orthohepevirus A. The global burden of infections from the two major genotypes (1 and 2) is estimated at 20 million per year, leading to 70, 000 deaths and 3, 000 stillbirths. HEV can be classified into four different genotypes from different geographical regions: genotype 1 (Asia), genotype 2 (Africa and Mexico), genotype 3 (Europe and North America) and genotype 4 (Asia).