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HIGD1A
This is a monoclonal antibody against a human HIG-1 polypeptide, the antibody binding to at least one epitope included in the amino acid sequence at positions 1-19 of a human HIG-1 polypeptide; Hypoxia-induced gene 1 (HIG-1) was reported as one of the genes induced under hypoxic conditions. HIG-1 is induced also by a decrease in glucose concentration. HIG-1 is considered to be localized in an inner membrane of mitochondria and to have a function of inhibiting hypoxia-induced cell death; however, the details thereof have yet to be revealed.
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Distal enterocytes, Distal tubular cells, Paneth cells)
Immune cell specificity
Immune cell enhanced (plasmacytoid DC)
Cell line specificity
Low cell line specificity
Interaction
Associates with cytochrome c oxidase (COX, complex IV); proposed complex component. Also associates with respiratory chain supercomplexes.
More Types Infomation
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- Species Reactivity: Human
- Type: ADCC enhanced antibody
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- Derivation: Hybridoma cell line
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA
- Mouse Anti-HIGD1A Antibody, mRNA (TAB-353CL-mRNA)
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- Species Reactivity: Human
- Anti-Human HIGD1A Recombinant Antibody (TAB-353CL)
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- Species Reactivity: Human
- Type: Antibody
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- Derivation: Hybridoma cell line
- Species Reactivity: Human
- Type: Mouse IgG3, κ
- Application: WB, ELISA
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- Derivation: Hybridoma cell line
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA
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For Research Use Only. Not For Clinical Use.