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HLA-A2-Mart-1 Complex

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Anti-HLA-A2-Mart-1 Complex Products

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For Research Use Only. Not For Clinical Use.


Background

Shared melanoma-associated antigens (Ag) (e.g., MART-1, gp100 and Tyrosinase) expressed among a variety of melanoma patients can be recognized by cytotoxic CD8+ T lymphocytes derived from melanoma patients. T-cell lines which specifically recognize the HLA restricted antigens expressed by tumor cells were generated and used to identify the genes encoding tumor antigens and the peptide epitopes derived therefrom.
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