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HLA-A2-Mart-1 Complex

Anti-HLA-A2-Mart-1 Complex Products
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- Species Reactivity: Human
- Type: Human IgG1, λ
- Application: ELISA, FC
- Human Anti-HLA-A2-Mart-1 Complex Recombinant Antibody (clone CLA12); scFv Fragment (HPAB-N0135-YC-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
- Human Anti-HLA-A2-Mart-1 Complex Recombinant Antibody (clone CLA12); Fab Fragment (HPAB-N0135-YC-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
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For Research Use Only. Not For Clinical Use.
Background
Shared melanoma-associated antigens (Ag) (e.g., MART-1, gp100 and Tyrosinase) expressed among a variety of melanoma patients can be recognized by cytotoxic CD8+ T lymphocytes derived from melanoma patients. T-cell lines which specifically recognize the HLA restricted antigens expressed by tumor cells were generated and used to identify the genes encoding tumor antigens and the peptide epitopes derived therefrom.