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IGSF5
Loading...Anti-IGSF5 Products
- Recombinant Anti-Human IGSF5 Antibody (MOB-1528z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, Neut, FuncS
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- Recombinant Anti-Human IGSF5 Antibody Fab Fragment (MOB-1528z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: FC, Neut, Funcs
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- Recombinant Anti-Human IGSF5 Antibody scFv Fragment (MOB-1528z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, FuncS
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity).
Predicted location
Membrane
Single cell type specificity
Cell type enriched (Syncytiotrophoblasts)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (T-47d)
Interaction
Interacts with MAGI1 at tight junctions, forms a tripartite complex with NPHS1. Interacts with LNX1 isoform 2 via its PDZ 2 domain, it may also interact with other isoforms containing this domain.
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