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IL22RA1

Anti-IL22RA1 Products
- Recombinant Anti-human IL22RA1 Antibody (MOB-564)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, Neut, FuncS
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: FC, IP, FuncS
- Recombinant Human Anti-human IL22RA1 Antibody Fab Fragment (MHH-564-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, IF, FuncS
- Recombinant Human Anti-human IL22RA1 Antibody scFv Fragment (MHH-564-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: Neut, IF, FuncS
- Recombinant Anti-human IL22RA1 Antibody Fab Fragment (MOB-564-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: FC, Neut, Funcs
- Recombinant Anti-human IL22RA1 Antibody scFv Fragment (MOB-564-S(P))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, FC, FuncS
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36.
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Proximal enterocytes, Distal enterocytes, Paneth cells, Exocrine glandular cells, Pancreatic endocrine cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (CACO-2, Hep G2, OE19)
Interaction
Heterodimer with IL10RB and with IL20RB. IL22 binding to heterodimer is greater than binding to IL22RA1 alone.
Molecular function
Receptor
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