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IQGAP2
Loading...Anti-IQGAP2 Products
- Anti-IQGAP2 Immunohistochemistry Kit (VS-0325-XY1136)
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- Species Reactivity: Human, Mouse, Rat
- Target: IQGAP2
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the IQGAP family. The encoded protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. This protein interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Early spermatids, Late spermatids)
Immune cell specificity
Immune cell enhanced (basophil)
Cell line specificity
Cell line enhanced (CACO-2, Hep G2, HMC-1, RPMI-8226, U-937)
Molecular function
Calmodulin-binding
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