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For Research Use Only. Not For Clinical Use.
Disease related genes, Transcription factors
Intracellular
Cell type enhanced (NK-cells)
Low immune cell specificity
Cell line enhanced (BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, GAMG)
Interacts with STAT2 in the cytoplasm. Forms the interferon-stimulated gene factor 3 complex (ISGF3) with the heterodimer STAT1:STAT2; upon stimulation.
Activator, DNA-binding