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IRX1
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of this gene is located on chromosome 13.
Protein class
Plasma proteins, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Group enriched (Breast myoepithelial cells, Breast glandular cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (AF22, REH, U-251 MG)
Molecular function
DNA-binding
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