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IVL

Anti-IVL Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin.
Protein class

Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Suprabasal keratinocytes, Squamous epithelial cells, Urothelial cells, Club cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (HaCaT, RT4, SK-BR-3)

Interaction

Directly or indirectly cross-linked to cornifelin (CNFN).

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