IZUMO1R

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For Research Use Only. Not For Clinical Use.


Background

Enables signaling receptor activity and signaling receptor binding activity. Involved in cell adhesion; fusion of sperm to egg plasma membrane involved in single fertilization; and sperm-egg recognition. Is active in plasma membrane. Is expressed in several structures, including alimentary system; endocrine gland; genitourinary system; immune system; and liver and biliary system.
Protein class

Transporters

Predicted location

Intracellular

Single cell type specificity

Not detected

Immune cell specificity

Not detected in immune cells

Cell line specificity

Not detected

Interaction

Monomer (PubMed:27309808). Interacts with IZUMO1; the interaction is direct. IZUMO1 and IZUMO1R/JUNO form a complex with 1:1 stoichiometry (PubMed:24739963, PubMed:27309818, PubMed:27309808).

Molecular function

Receptor

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