IgE
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- Host Species: Human
- Specificity: Human
- Type: Humanized antibody
- Classification: Fc glycosylation/Non fucosylated
- Glycosylation site: Fc region
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- Host Species: Human
- Specificity: Human
- Type: Humanized antibody
- Classification: Fc glycosylation/Non fucosylated
- Glycosylation site: Fc region
-
- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Classification: Fab glycosylation/Fc glycosylation
- Glycosylation site: aa73-75 of VH
aa301-303 of CH - Glycoform (ratio): G0
-
- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Classification: Fab glycosylation/Fc glycosylation
- Glycosylation site: aa73-75 of VH
aa301-303 of CH - Glycoform (ratio): G0
-
- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Classification: Fab glycosylation/Fc glycosylation
- Glycosylation site: aa73-75 of VH
aa301-303 of CH - Glycoform (ratio): G1
-
- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Classification: Fab glycosylation/Fc glycosylation
- Glycosylation site: aa73-75 of VH
aa301-303 of CH - Glycoform (ratio): G2
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For Research Use Only. Not For Clinical Use.
Background
IgE also has an essential role in type I hypersensitivity, which manifests in various allergic diseases, such as allergic asthma, most types of sinusitis, allergic rhinitis, food allergies, and specific types of chronic urticaria and atopic dermatitis. IgE also plays a pivotal role in responses to allergens, such as: anaphylactic reactions to drugs, bee stings, and antigen preparations used in desensitization immunotherapy.


Asthma