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Intermediate Neurofilament
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- Intermediate Neurofilament Antibody Panel (NEFH, NEFL, NEFM) (VS-0725-YC48)
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- Species Reactivity: Human
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For Research Use Only. Not For Clinical Use.
Background
Intermediate neurofilaments (NFs) are a specialized class of intermediate filaments found exclusively in neurons, forming a crucial component of the neuronal cytoskeleton. Along with microtubules and actin filaments, they provide mechanical strength, shape, and stability to neurons, particularly within the long, slender axons where they are exceptionally abundant. Neurofilaments are essential for maintaining axonal caliber, which directly influences the speed of nerve impulse conduction.