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JCHAIN

Anti-JCHAIN Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component
Protein class

Plasma proteins

Predicted location

Secreted

Single cell type specificity

Cell type enriched (Plasma cells)

Immune cell specificity

Group enriched (memory B-cell, plasmacytoid DC, naive B-cell)

Cell line specificity

Cell line enhanced (Daudi, Karpas-707, RPMI-8226, U-266/70, U-266/84, U-698)

Interaction

Part of the secretory IgA (sIgA) complex that consists of two, four or five IgA monomers, and two additional non-Ig polypeptides, namely the JCHAIN and the secretory component (the proteoytic product of PIGR).

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