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JPH2

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Anti-JPH2 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


JPH2 (Junctophilin 2) is a Protein Coding gene encodes the protein which is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. Diseases associated with JPH2 include Cardiomyopathy, Familial Hypertrophic, 17 and Lung Abscess.
Protein class

Disease related genes, Potential drug targets, Transporters

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enriched (Cardiomyocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (CACO-2, EFO-21, fHDF/TERT166, HeLa, SiHa)

Interaction

Interacts with TRPC3 (PubMed:20095964). [Junctophilin-2 N-terminal fragment]: Interacts with MEF2C (By similarity).

Molecular function

Developmental protein, DNA-binding, Repressor

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