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JPH2
JPH2 (Junctophilin 2) is a Protein Coding gene encodes the protein which is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. Diseases associated with JPH2 include Cardiomyopathy, Familial Hypertrophic, 17 and Lung Abscess.
Protein class
Disease related genes, Potential drug targets, Transporters
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enriched (Cardiomyocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (CACO-2, EFO-21, fHDF/TERT166, HeLa, SiHa)
Interaction
Interacts with TRPC3 (PubMed:20095964). [Junctophilin-2 N-terminal fragment]: Interacts with MEF2C (By similarity).
Molecular function
Developmental protein, DNA-binding, Repressor
More Types Infomation
- Rabbit Anti-JPH2 Polyclonal Antibody (MRO-1988-CN) (MRO-1988-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
- Recombinant Mouse Anti-JPH2 Monoclonal Antibody (3-2) (MRO-0889-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG1
- Application: WB, IF, IHC, FC
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For Research Use Only. Not For Clinical Use.